About 1 out of 3 people with
lupus produce an
antibody that attacks certain blood-clotting factors,
which can cause the blood to clot easily.footnote 1 A person who has this antibody and has had blood clots is said to have antiphospholipid antibody syndrome. This
can lead to mild or severe blood-clotting complications, including:
A blood test can detect antiphospholipid antibodies. When diagnosed, the condition is usually treated with
anticoagulants. Pregnant women with antiphospholipid
antibody syndrome need to be closely monitored.
CitationsCrow MK (2016). Systemic lupus erythematosus. In L Goldman, A Shafer, eds., Goldman-Cecil Medicine, 24th ed., vol. 2, pp. 1769-1777. Philadelphia: Saunders.
ByHealthwise StaffPrimary Medical ReviewerAnne C. Poinier, MD - Internal MedicineMartin J. Gabica, MD - Family MedicineE. Gregory Thompson, MD - Internal MedicineKathleen Romito, MD - Family MedicineSpecialist Medical ReviewerNancy Ann Shadick, MD, MPH - Internal Medicine, Rheumatology
Current as ofOctober 31, 2016
Current as of:
October 31, 2016
Anne C. Poinier, MD - Internal Medicine & Martin J. Gabica, MD - Family Medicine & E. Gregory Thompson, MD - Internal Medicine & Kathleen Romito, MD - Family Medicine & Nancy Ann Shadick, MD, MPH - Internal Medicine, Rheumatology
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Last modified on: 8 September 2017